The Technology

Solution KB-00 is a multi-component disinfectant with a myriad of applications. It provides a suitable concentrate of organo-metalic compounds that form suitable disinfectants and sterilants upon admixing it with water or other aqueous sources. The bactericidal agents used are stabilized hydrogen peroxide and chelated silver ions that work in a synergistic fashion so as to disrupt biological activities of microorganisms. Due to its proprietary nature, it has been awarded a United States Patent # 6,242,009, and it is currently being patented in more than twenty countries, and is available on the PCT (Patent Cooperation Treaty) Web Site, and has the number WO 00/62618. In addition, Solution KB-00 has been approved by the USFDA (United States Food & Drug Administration), and is now available on the FDA effective notification Internet site at http://www.cfsan.fda.gov/~dms/opa-fcn.html and is assigned the Numbers 295 and 296. It is also noteworthy to mention here that these approvals are novel since they constitute precedence in that it is the first time that the USFDA approves silver and hydrogen peroxide as antimicrobial agents to be used as direct food additives.
Solution KB-00 is a new generation of ecologically non-toxic antiseptics and disinfectants that are highly effective against a broad spectrum of pathogenic microorganisms. These compounds differ from conventional chemical disinfectants and sterilants since they do not contain poisonous substances such as aldehydes, phenols, chlorine, etc. Solution KB-00 is not only a disinfectant but also an effective sterilant; as the name implies it can completely destroy pathogenic microorganisms. Such compound offer many advantages over conventional ones.

Resumé About The Molecule/Mode Of Action

Physicochemical Data

FORM		Clear liquid. In its concentrated form it has a fainted smell; however, in its at use concentration, it is tasteless and odorless.
MOLECULAR WEIGHT		23.8 g-mole/mole
SOLUBILITY		miscible in all proportions
DENSITY		1.195 g/ml
VAPOR DENSITY		2.18E-5 g/ml
VISCOCITY		1.2 cp
BOILING POINT		114ºC
MELTING POINT		-52º C
pH		< 1.3
BIO-DEGRADABILITY		Hydrogen peroxide which is its major constituent is readily decompose to water and oxygen; other ingredients are readily biodegradable. All of silver ions present will precipitate as silver salts.
CARCINOGEN STATUS		Non-mutagenic and non-carcinogenic
COMBUSTABILITY		Non-flammable. Contact with metals, metal ions, organics, wood, dust, shavings, or dry vegetables may cause combustion.
REACTIVITY		Do not drop or drag containers; solution is shock sensitive. This material is chemically stable with additives.
BLEACHING		At use concentration is non-bleaching and non-discoloring.
NEUTRALIZATION		Can be readily neutralized with sodium bisulphite (NaHSO3), producing sodium bisulphate (NaHSO4).

Toxicity

A. Active Ingredients

Hydrogen peroxide & Silver:

Hydrogen peroxide decomposes readily upon contact with food and it is degraded to H2O and O2 which should not present any toxicological concerns. The concentration of silver in attaining the intended technical effect should not present any toxicological concerns since its concentration is comparable with that of USFDA (United States Food & Drug Administration), USDA (United States Department of Agriculture) USEPA (United States Environmental Protection Agency) and the WHO (World Health Organization) standards for silver regulations. It is especially notable to mention here that, from an ecological perspective, the decomposition end-products of Solution KB-00 is mainly water and trace elements that are harmless to living organisms.

B. Inactive Ingredients

All inactive ingredients present in Solution KB-00 are basic constituent of the human food diet. All are considered as indirect food additives, and it is generally recognized as safe (GRAS) by the USFDA.

Advantages

There are numerous advantages related to the present chemical, including but not restricted to the following:

1) Offer rapid sterilization and disinfection
2) Clear, tasteless and odorless compounds
3) It is harmless to humans, plants, vegetation and aquatic life
4) It has a broad spectrum of germicidal activities
5) Numerous applications
6) It is environmentally safe and friendly
7) Non-carcinogenic or mutagenic
8) Inexpensive
9) Can be applied using conventional spraying and fogging techniques
10) It does not decompose to produce harmful substances or by-products
11) In its conventional use, it is neither harmful nor irritating

Applications

The table below depicts the present biocide's specific usages and applications disinfectants, respectively

General Usage		Defined Usage
Drinking water	:	Additives for concentrates Well disinfectant Drinking water treatment Emergency water Pipe-system disinfectant
Winery	:	Appliances & Installations
Breweries	:	Pipe-systems
Soft drink production & bottling plants	:	Hot water areas Filters Resting disinfectant Fresh water zones
Baby bottles	:	Disinfectant
Swimming pools	:	Swimming pools Whirlpools Sauna Surface disinfectant Anti-fungus
Food & beverage industry	:	General disinfectant Conservation of fish product Tined foods Fruit processing Fresh fruit Slaughter houses Meat factories
Pesticides	:	Environmentally friendly for The prevention of pre-and-post Harvest diseases
Dairies	:	Installations Milk & milk products Ice-cream production
Farming	:	Drinking water Installation
Fish farming	:	Installations Fish water
Hospitals	:	Installations Laundry Immersion Hand disinfectant
Pharmaceutical & chemical Industry	:	Installations Product preservation
Air conditioning	:	Filter, water Pipes
Cooling towers	:	Radiators
Travel & camping	:	General disinfectant
Household	:	General disinfectant
Armed forces	:	Installations Water treatment
Industrial Biofouling	:	Refineries, piping systems, etc.

Microbicidal Effect

Solution KB-00 has been tested against a broad spectrum of microorganisms. This includes testing it in water, on surfaces, and on food, including agricultural crops as a pesticide. These protocols include determining Minimum Inhibitory Concentration (MIC), Acute Kill Experiments and Bacterial Enumeration. Collectively, Solution KB-00 has been proven to be a potent and effective microbicidal agent if applied within certain recommended levels of concentration. The present complex was found to be extremely attractive to be used for agricultural crops and products. This emanates from the fact that there are no known virucides for agricultural products, making the present invention to be the first of its kind for such applications.

Comparison With Conventional Disinfectants

COMPARISON WITH VARIOUS TYPES OF DISINFECTANTS
Evaluation criteria	Phenols	Aldehydes	Halogens	Solution KB-00
Surface behavior	Absorbed on rubber and plastics	Unsatisfactory	Good	Very Good
Odor	Strong	Pungent	Strong	Odorless
Tolerance to skin	Fair	irritant to skin & eyes	irritant to skin & eyes	Very good
Carcinogenety	Yes, proven	Yes, proven	Yes, in the form of chloroform	None
Universal use	Limited	Limited	Moderate	Very good

Handling Advantages

Solution KB-00 is miscible in water in all proportions

Solution KB-00 does not foam

Solution KB-00 leaves no coating on disinfected surfaces

Solution KB-00 does not bleach or discolor disinfected surfaces

 

Storage & Stability

Storage of KB-00
According to our MSDS-stored in a dark place with a temperature range of 5-25°C with a maximum storage time of 6 months. Since ultraviolet rays could cause decomposition of end product, all storage containers should be impervious to light. Storage tanks can be made from materials such as borosilicate glasses, pure aluminum (99.5% aluminum with a Cu and Fe content = 0.002%), stainless steel, high density polyethylene, and polyvinylchloride (PVC) can all be used as long as they don't contain plasticisers and/or pigments that might interfere with the end product.
Stability of KB-00:

Biological experiments have revealed that there was no significant change of Solution KB-00 efficacy after six month from making the batches. Stability larger than six months are of no consequence since Solution KB-00 will generally be used within 3 months of production.